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Risk factors for chronic graft-versus-host disease after anti-thymocyte globulin-based haploidentical

Meng Lv, Xiaohui Zhang, Lanping Xu, Yu Wang, Chenhua Yan, Huan Chen, Yuhong Chen, Wei Han, Fengrong Wang, Jingzhi Wang, Kaiyan Liu, Xiaojun Huang, Xiaodong Mo

Frontiers of Medicine 2019, Volume 13, Issue 6,   Pages 667-679 doi: 10.1007/s11684-019-0702-z

Abstract: Chronic graft-versus-host disease (cGVHD) is a major complication following unmanipulated haploidentical

Keywords： acute graft-versus-host disease     chronic graft-versus-host disease     National Institutes of Health consensus    

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Immune Regulatory Cell Biology and Clinical Applications to Prevent or Treat Acute Graft-Versus-HostDisease Review

Bruce R. Blazar

Engineering 2019, Volume 5, Issue 1,   Pages 98-105 doi: 10.1016/j.eng.2018.11.016

Abstract:

The most common approaches to prevent and treat graft-versus-host disease (GVHD) are intended to depletenot result in tolerance (i.e., nonresponsiveness) of donor T cells to conditioning regimen-resistant hostfrequencies, methods to isolate and expand these cells have permitted their supplementation to the donor graft

Keywords： Graft-versus-host disease (GVHD)     Immune regulatory cells     Cell therapy    

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Graft versus host disease after liver transplantation: A case report

Peng-Ji GAO, Xi-Sheng LENG, Dong WANG, Guang-Ming LI, Lei HUANG, Jie GAO, JI-Ye ZHU,

Frontiers of Medicine 2010, Volume 4, Issue 4,   Pages 469-472 doi: 10.1007/s11684-010-0120-8

Abstract: In documenting clinical experience in the diagnosis and treatment of graft host disease (GVHD), we retrospectively

Keywords： liver transplantation     graft versus host disease    

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Everyone has a donor: contribution of the Chinese experience to global practice of haploidentical hematopoietic stem cell transplantation

Meng Lv, Yingjun Chang, Xiaojun Huang

Frontiers of Medicine 2019, Volume 13, Issue 1,   Pages 45-56 doi: 10.1007/s11684-017-0595-7

Abstract: individualized conditioning regimens, donor selection based on non-HLA systems, risk-directed strategies for graft-versus-hostdisease and relapse, and infection management.

Keywords： haploidentical hematopoietic stem cell transplantation     conditioning     graft-versus-host disease     relapse    

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Gene and protein expression of proteinase-activated receptor-1, 2 in a murine model of acute graft hostdisease

Quan LI MD , Weiming LI MD , Ping ZOU MD , Jian ZHANG BM ,

Frontiers of Medicine 2009, Volume 3, Issue 3,   Pages 309-315 doi: 10.1007/s11684-009-0043-4

Abstract: However, little is known about the function of PAR-1, 2 in acute graft host disease (GVHD).

Keywords： graft vs host disease     proteinase-activated receptor     murine model     hematopoietic stem cell transplantation    

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Robotic distal pancreatectomy versus conventional laparoscopic distal pancreatectomy: a comparative study

Eric C. H. Lai,Chung Ngai Tang

Frontiers of Medicine 2015, Volume 9, Issue 3,   Pages 356-360 doi: 10.1007/s11684-015-0404-0

Abstract:

Robotic system has been increasingly used in pancreatectomy. However, the effectiveness of this method remains uncertain. This study compared the surgical outcomes between robot-assisted laparoscopic distal pancreatectomy and conventional laparoscopic distal pancreatectomy. During a 15-year period, 35 patients underwent minimally invasive approach of distal pancreatectomy in our center. Seventeen of these patients had robot-assisted laparoscopic approach, and the remaining 18 had conventional laparoscopic approach. Their operative parameters and perioperative outcomes were analyzed retrospectively in a prospective database. The mean operating time in the robotic group (221.4 min) was significantly longer than that in the laparoscopic group (173.6 min) (P = 0.026). Both robotic and conventional laparoscopic groups presented no significant difference in spleen-preservation rate (52.9% vs. 38.9%) (P = 0.505), operative blood loss (100.3 ml vs. 268.3 ml) (P = 0.29), overall morbidity rate (47.1% vs. 38.9%) (P = 0.73), and post-operative hospital stay (11.4 days vs. 14.2 days) (P = 0.46). Both groups also showed no perioperative mortality. Similar outcomes were observed in robotic distal pancreatectomy and conventional laparoscopic approach. However, robotic approach tended to have the advantages of less blood loss and shorter hospital stay. Further studies are necessary to determine the clinical position of robotic distal pancreatectomy.

Keywords： distal pancreatectomy     pancreatic neoplasm     robotic surgery    

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Performance and synergistic effect of phenolic and thio antioxidants in ABS graft copolymers

Gongsheng LI, Xuhong GUO, Wang NA, Diancheng HAO, Mingyao ZHANG, Huixuan ZHANG, Jun XU

Frontiers of Chemical Science and Engineering 2011, Volume 5, Issue 1,   Pages 26-34 doi: 10.1007/s11705-010-0531-8

Abstract: effect of phenolic and thio antioxidants on the stabilization of acrylonitrile-butadiene-styrene (ABS) graft

Keywords： antioxidant     ABS graft copolymers     synergistic effect    

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Separation of epigallocatechin-3-gallate from crude tea polyphenols by using Cellulose diacetate graft

Hong ZHU, Peiyong QIN

Frontiers of Chemical Science and Engineering 2011, Volume 5, Issue 3,   Pages 330-338 doi: 10.1007/s11705-010-1104-6

Abstract: This study demonstrates a new Cellulose diacetate graft -cyclodextrin (CDA- -CD) copolymer asymmetricThe graft copolymer, CDA- -CD, was synthesized by prepolymerization of cellulose diacetate (CDA) andThe influences of the HDI/CDA mass ratio and the catalyst mass fraction on the -CD graft yield wereThe effects of the -CD graft yield and the concentration of the polymer cast solution on the separationUnder optimum conditions of a -CD graft yield of 24.21 wt-% and a polymer concentration of 13 wt-%,

Keywords： (-)-epigallocatechin-3-gallate (EGCG)     tea polyphenols     CDA-β-CD    

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AMMONIA DISPERSION FROM MULTI-FLOOR VERSUS STANDARD SINGLE-FLOOR PIG PRODUCTION FACILITIES BASED ON COMPUTATIONAL

Frontiers of Agricultural Science and Engineering 2023, Volume 10, Issue 3,   Pages 374-389 doi: 10.15302/J-FASE-2023501

Abstract:

● NH3 dispersion from a multi-floor pig building was compared to a single-floor building.

Keywords： pig building     computational fluid dynamics     ammonia     dispersion    

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Integrated analysis of gut microbiome and host immune responses in COVID-19

Frontiers of Medicine 2022, Volume 16, Issue 2,   Pages 263-275 doi: 10.1007/s11684-022-0921-6

Abstract: Emerging evidence indicates that the gut microbiome contributes to the host immune response to infectiousHere, to explore the role of the gut microbiome in the host immune responses in COVID-19, we conductedWe identified the abundance of some gut microbes altered post-SARS-CoV-2 infection and related to diseaseWe further analyzed the correlation between the abundance of gut microbes and host responses, and obtainedhighlighted a potential regulatory role of severity related gut microbes in the immune response of host

Keywords： COVID-19     SARS-COV-2     gut microbiome     immune response    

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Peridynamics versus XFEM: a comparative study for quasi-static crack problems

Jinhai ZHAO, Hesheng TANG, Songtao XUE

Frontiers of Structural and Civil Engineering 2018, Volume 12, Issue 4,   Pages 548-557 doi: 10.1007/s11709-017-0434-6

Abstract: Peridynamics (PD) is a nonlocal continuum theory based on integro-differential equations without spatial derivatives. The fracture criterion is implicitly incorporated in the PD theory and fracture is a natural outcome of the simulation. However, capturing of complex mixed-mode crack patterns has been proven to be difficult with PD. On the other hand, the extended finite element method (XFEM) is one of the most popular methods for fracture which allows crack propagation with minimal remeshing. It requires a fracture criterion which is independent of the underlying discretization though a certain refinement is needed in order to obtain suitable results. This article presents a comparative study between XFEM and PD. Therefore, two examples are studied. The first example is crack propagation in a double notched specimen under uniaxial tension with different crack spacings in loading direction. The second example is the specimens with two center cracks. The results show that PD as well as XFEM are well suited to capture this type of behaviour.

Keywords： XFEM     peridynamic     bilateral crack     parallel double cracks     nonlocal theory    

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Synthesis and thermosensitive behavior of dextran graft copolymers containing poly (N-vinylcaprolactam

SHI Huangying, CHEN Wenjuan, ZHANG Liming

Frontiers of Chemical Science and Engineering 2007, Volume 1, Issue 1,   Pages 72-75 doi: 10.1007/s11705-007-0015-7

Abstract: New graft copolymers were synthesized by grafting N-vinylcaprolactam onto dextran.By optical transmittance measurements, it was found that the aqueous solutions of these graft copolymerstemperature-dependent transmittance change due to the introduction of thermosensitive poly (-vinylcaprolactam) graftMoreover, the lower critical solution temperature (LCST) of the graft copolymer in aqueous solution was

Keywords： transmittance     copolymer concentration     LCST     temperature     elemental    

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Machine perfusion versus cold storage of livers: a meta-analysis

Sushun Liu,Qing Pang,Jingyao Zhang,Mimi Zhai,Sinan Liu,Chang Liu

Frontiers of Medicine 2016, Volume 10, Issue 4,   Pages 451-464 doi: 10.1007/s11684-016-0474-7

Abstract:

Different organ preservation methods are key factors influencing the results of liver transplantation. In this study, the outcomes of experimental models receiving donation after cardiac death (DCD) livers preserved through machine perfusion (MP) or static cold storage (CS) were compared by conducting a meta-analysis. Standardized mean difference (SMD) and 95% confidence interval (CI) were calculated to compare pooled data from two animal species. Twenty-four studies involving MP preservation were included in the meta-analysis. Compared with CS preservation, MP can reduce the levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), lactate dehydrogenase (LDH), and hyaluronic acid (HA) and the changes in liver weight. By contrast, MP can enhance bile production and portal vein flow (PVF). Alkaline phosphatase (ALP) levels and histological changes significantly differed between the two preservation methods. In conclusion, MP of DCD livers is superior to CS in experimental animals.

Keywords： machine perfusion     cold storage     DCD     meta-analysis    

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INTERFERENCE BY NON-HOST PLANT ROOTS AND ROOT EXUDATES IN THE INFECTION PROCESSES OF PHYTOPHTHORA NICOTIANAE

Frontiers of Agricultural Science and Engineering 2021, Volume 8, Issue 3,   Pages 447-459 doi: 10.15302/J-FASE-2021399

Abstract: The interactions between non-host roots and pathogens may be key in the inhibition of soilborne pathogensThese interspecific interactions between non-host roots and pathogens were found to be an important factor

Keywords： fennel and tobacco rotation     infection behavior     Phytophthora nicotianae     reactive oxygen species     vanillin    

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State versus private sector provision of water services in Armenia

Naira HARUTYUNYAN

Frontiers of Environmental Science & Engineering 2012, Volume 6, Issue 5,   Pages 620-630 doi: 10.1007/s11783-012-0425-8

Abstract: Despite increasing advocacy and adaptation of public-private model of water governance worldwide since the 1990s, today only 5% of the world’s population is served by water utilities with private involvement. The present article examines the experience of the water sector in Armenia with private sector participation. The study describes the process of the introduction of public-private partnerships in the water sector and focuses on analyzing the impact of privatization on water utility performance. The analysis employs the partial indicator method for evaluating the impacts in relation to operational, finance, and environmental performance, done by drawing on the database for the five water companies in Armenia. The empirical evidence shows that private participation in general led to improved overall performance. In particular, private involvement resulted in increased operational efficiency in terms of labor productivity, water metering, continuity of service, and revenue collection efficiency. There were mixed improvements in the operating cost coverage ratio. As for environmental performance, there were gains in the reduction of residential water consumption, accompanied, however, by an increase in non-revenue water.

Keywords： water governance     water privatization     public-private partnership     operational efficiency     Armenia     transition economy    

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Title Author Date Type Operation

Risk factors for chronic graft-versus-host disease after anti-thymocyte globulin-based haploidentical

Meng Lv, Xiaohui Zhang, Lanping Xu, Yu Wang, Chenhua Yan, Huan Chen, Yuhong Chen, Wei Han, Fengrong Wang, Jingzhi Wang, Kaiyan Liu, Xiaojun Huang, Xiaodong Mo

Journal Article

Immune Regulatory Cell Biology and Clinical Applications to Prevent or Treat Acute Graft-Versus-HostDisease

Bruce R. Blazar

Journal Article

Graft versus host disease after liver transplantation: A case report

Peng-Ji GAO, Xi-Sheng LENG, Dong WANG, Guang-Ming LI, Lei HUANG, Jie GAO, JI-Ye ZHU,

Journal Article

Everyone has a donor: contribution of the Chinese experience to global practice of haploidentical hematopoietic stem cell transplantation

Meng Lv, Yingjun Chang, Xiaojun Huang

Journal Article

Gene and protein expression of proteinase-activated receptor-1, 2 in a murine model of acute graft hostdisease

Quan LI MD , Weiming LI MD , Ping ZOU MD , Jian ZHANG BM ,

Journal Article

Robotic distal pancreatectomy versus conventional laparoscopic distal pancreatectomy: a comparative study

Eric C. H. Lai,Chung Ngai Tang

Journal Article

Performance and synergistic effect of phenolic and thio antioxidants in ABS graft copolymers

Gongsheng LI, Xuhong GUO, Wang NA, Diancheng HAO, Mingyao ZHANG, Huixuan ZHANG, Jun XU

Journal Article

Separation of epigallocatechin-3-gallate from crude tea polyphenols by using Cellulose diacetate graft

Hong ZHU, Peiyong QIN

Journal Article

AMMONIA DISPERSION FROM MULTI-FLOOR VERSUS STANDARD SINGLE-FLOOR PIG PRODUCTION FACILITIES BASED ON COMPUTATIONAL

Journal Article

Integrated analysis of gut microbiome and host immune responses in COVID-19

Journal Article

Peridynamics versus XFEM: a comparative study for quasi-static crack problems

Jinhai ZHAO, Hesheng TANG, Songtao XUE

Journal Article

Synthesis and thermosensitive behavior of dextran graft copolymers containing poly (N-vinylcaprolactam

SHI Huangying, CHEN Wenjuan, ZHANG Liming

Journal Article

Machine perfusion versus cold storage of livers: a meta-analysis

Sushun Liu,Qing Pang,Jingyao Zhang,Mimi Zhai,Sinan Liu,Chang Liu

Journal Article

INTERFERENCE BY NON-HOST PLANT ROOTS AND ROOT EXUDATES IN THE INFECTION PROCESSES OF PHYTOPHTHORA NICOTIANAE

Journal Article

State versus private sector provision of water services in Armenia

Naira HARUTYUNYAN

Journal Article